Dermamelan

KFMPIG0012/2109 mesoestetic Pharma Group, s.l. C/ Tecnologia, 25 08840 - Viladecans (Barcelona) Tel. +34 93 325 20 30 www.mesoestetic.com made in Spain 1. Study invitro on the inhibitionof tyrosinasewith [syn]pigmenTarget ® .UnitofbiotechnologyofmesoesteticPharmaGroupS.L. (INF265.UB.SEP.2020). 2. Enzymeassayon theactivityof tyrosinasewith melaphenone ® . Unit of biotechnology of mesoestetic Pharma Group S.L. (INF266.UB.MAY.2021). 3. Study on the dendricity of melanocytes stimulated with IBMX, an activator of the α -MSH pathway, and treated with dermamelan ® by microscopy (Olympus CKX41). Unit of biotechnology of mesoestetic Pharma Group S.L. (INF278.UB.MAY.2021). 4. Study on the genetic expression of TRP-2 /DCT by qPCR in culture of melanocytes stimulated with ET-1 and treated with dermamelan ® . Unit of biotechnology of mesoestetic Pharma Group S.L. (INF274.UB.FEB.2021). 5. Study on the genetic expression of COX- 2 by qPCR in culture of fibroblasts stimulated with IL-1 and treated with dermamelan ® . Unit of biotechnology of mesoestetic Pharma Group S.L. (INF275.UB.MAR.2021). 6. Study on the genetic expression of TIMP3 by qPCR in culture of fibroblasts treated with dermamelan ® . Unit of biotechnology of mesoestetic Pharma Group S.L. (INF279.UB.MAY.2021). 7. Clinical study on the efficacy of dermamelan ® . Medical Unit of mesoestetic Pharma Group S.L. 2020. 8. Skin Therapy Lett. 2016 Jan;21(1):1-7. Formulae with synergistic and complementary action in the different targets of the pigmentation process. An evolution in the field of hyperpigmentation using the latest medical-scientific developments. Systems of vehiculation and penetration for maximum efficiency of the active ingredients. The only depigmentation treatment with all-in-one corrective, regulating action at two levels. dermamelan ®