dermamelan@ intimate-EN

dermamelan intimate ® : studies in vitro Evaluation of the efficacy of [meso] intimate system® Evaluation of the efficacy of home depigmenting gel cream intimate medical solutions Inhibition of melanin production in a melanocyte culture. Inhibition of the production of IL-6 , the main inflammatory marker, evidencing the regulatory capacity of the inflammatory component associated with hyperpigmentation. control culture induction culture culture with [meso] intimate system ® 100 80 60 40 20 0 % melanin synthesis -100 % control culture induction culture culture with [GL] Inflamm ® 100 80 60 40 20 0 % IL-6 synthesis -88 % IL-6 - 68 % - 86 % - 60 % > DEPIGMENTING ACTION > BARRIER FUNCTION Inhibition of melanosomes transfer (13) Reduction of tyrosinase enzyme (12) Reduction of melanin formed (14) Transepidermal water loss (TEWL*) (15) studies in vitro study in vivo - 27 %