dermamelan@ intimate-EN

mesofiller ® sensitive: vaginal health parameters (4) [HA 20 ml] Gloria Bachmann Vaginal Health Index (VHI): The results show a significant improvement in the functional parameters of the vagina (elasticity, flow volume, epithelial integrity, pH, hydration) Nugent index: A reduction of this index shows a re-establishment of normal values of non-pathological bacteria . Measured by cytology. Visual analogue scale (VAS): Measurement of pain reduction during the gynaecological examination after the treatment. Evaluation of satisfaction degree Patient satisfaction questionnaire Vaginal maturation index (VMI): The result shows the re-establishment of the number of superficial and intermediate cells , which means an improvement of vulvovaginal atrophy. Measured by cytology. Sexual function (FSFI): A reduction in the FSFI index shows a significant improvement in the parameters of sexual arousal, orgasm, satisfaction. -84% +97% intimate medical solutions D0 Pre-treatment D0 Pre-treatment Improvement of VMI % of patients D30 Post-treatment D0 Pre-treatment D60 Post-treatment D60 Post-treatment D60 Post-treatment No VMI improvement (p < 0.01) (p = 0.05) (p < 0.01) (p < 0.01) (p < 0.01) 23 21 19 17 15 13 11 9 7 5 0 25 50 75 100 6 5 4 3 2 1 0 27 22 17 12 7 2 Mean VHI Nugent index Mean FSFI -33 % -85 % 68 % 32 %

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