AGE ELEMENT Personalised Anti-aging Science FR

KPPAGE0005/2103 mesoestetic Pharma Group, s.l. C/ Tecnologia, 25 08840 - Viladecans (Barcelona) Tel. +34 93 325 20 30 www.mesoestetic.com made in Spain Formules bénéficiant de la technologie brevetée [meso]epigen system™ pour combattre le vieillissement dès son origine. Système professionnel anti-âge de dernière génération inspiré de la technologie médico-esthétique la plus avancée. Protocole 100 % personnalisé à partir d’un système de diagnostic exclusif : age element diagnosis system™ Une solution complète anti-âge offrant toutes les phases indispensables et des séances personnalisées qui permettent de construire des expériences uniques lors de chaque séance. antiaging professional solutions 1. Rando, T. A. and Chang, H. Y. Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock. Cell. 2012; 148 (1-2): 46. 2. Masood A. Shammas. Telomeres, lifestyle, cancer, and aging. Curr Opin Clin Nutr Metab Care. 2011 Jan; 14(1): 28–34. 3. E.Michishita, R. A. McCord, E. Berber, M. Kioi, H. Padilla- Nash, M. Damian, P. Cheun, R. Kusumoto, T. L. A. Kawahara, J. Carl Barrett, H. Y. Chang, V. A. Bohr, T. Ried, O. Gozani, and K. F.Chua. SIRT6 is a histoneH3 lysine9deacetylase thatmodulates telomericchromatin.Nature.2008March27;452(7186):492–496. 4. Maslinicacid:Thesecretof longevity,E.Grau,Cosmetic Industry,002; 2017. 5. Y.-h.chen,L.huang,Z.-h.wen, C.zhang,C.-h. liang,S.-t. lai,L.-z. luo,Y.-y.wang,G.-h.Wang.Skinwhiteningcapabilityofshikimicacidpathwaycompounds.EurRevMedPharmacolSci.2016;21214-12200: 6. E.Schadich,J.HlaváI,T.Volná,L.Varanasi,M.Hajdúch, and P. DDubák. Effects of Ginger Phenylpropanoids and Quercetin on Nrf2-A Pathway in Human BJ Fibroblasts and HaCaT Keratinocytes. Hindawi Publishing Corporation, BioMed Research International. 2016, 2173275, 6 pages. 7. Shin-Hae Lee, Ji-Hyeon Lee, Hye-Yeon Lee, and Kyung-Jin Min.BMB Rep. Sirtuin signaling in cellular senescence and aging. 2019 Jan; 52(1): 24–34. 8. N. Yuan, X. Zhang, N. Sengupta, W. S. Lane2, and E. Seto. sIRT1 regulates the function of the Nijmegen breakage syndrome protein. Mol Cell. 2007July 6; 27(1): 149–162. 9. W. Fan and J. Luo. SIRT1 regulates UV-induced DNA repair through deacetylating XPA. Mol Cell. 2010; 39: 247–258. 10. In Hye Lee, L. Cao, R. Mostoslavsky, D. B. Lombard, J. Liu, N. E. Bruns, M. Tsokos, Fr. W. Alt, and T. Finkel.A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy .PNAS. 2008; 105(9) 3374–3379.